DPP-4 Inhibitors - Regulate Blood Glucose Levels - Regner Health Solutions
Combination therapy with DPP-4 inhibitors and metformin is particularly effective in regulating blood glucose levels. Metformin, a widely used oral antidiabetic agent, primarily decreases hepatic glucose production. When used together, DPP-4 inhibitors enhance the effects of metformin by increasing the concentrations of GLP-1 and GIP, which promote insulin secretion and decrease glucagon release. This combined approach has shown more significant reductions in HbA1c levels than medication alone. Notable differences have been observed in the effects of different DPP-4 inhibitors on glucagon levels. Some DPP-4 inhibitors have been found to suppress glucagon secretion to a greater extent than others. This is important because glucagon, a hormone released by the pancreas, raises blood glucose levels by promoting the breakdown of glycogen in the liver. Therefore, DPP-4 inhibitors that effectively lower glucagon levels contribute to improved blood glucose control. Learn more about DPP-4 inhibitors and other services we offer: regnerhealthsolutions.com/dpp4-inhibitors/
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